Endocrine Abstracts

Introduction: Hypoglycemia is common in diabetic patients as an adverse effect of their medication. A minority of hypoglycemia occurs in non-diabetic patients. This spontaneous hypoglycemia defined by the Whipple’s triad results from organic (non-reactive) or functional (reactive) causes, and in few cases, a factitious hypoglycemia, posing an etiological problem. The aim of our study was to assess clinical and biological features of non-reactive hypoglycemia in non-diabe...

Introduction: CD8+ T-cell deficiency is a feature of many chronic autoimmune diseases. Its association with vitamin D deficiency was described and it has been suggested that vitamin d deficiency contribute to the increase of the incidence and the progression of autoimmune diseases.Herein we report a case of hypopituitarism and vitamin D deficiency in a patient with CD8+ T-cell deficiency.Observation: A 28-year-old woman was...

Introduction: Levothyroxine is the treatment of hypothyroidism, achieving normal thyroid stimulating hormone (TSH) levels. The optimal dose of Levothyroxine may be affected by several factors such as age, gender, body weight, patient’ compliance, some medical disorders and drugs intake. Persistent hypothyroidism secondary to non compliance is rare and represents a diagnostic challenge.The aim of this study was to describe cases with refractory hypo...

Background: Common Variable Immunodeficiency syndrome (CVID), the most common symptomatic immunodeficiency in aduIts, is characterized by diminished levels of IgG, IgA and/or IgM, and recurrent bacterial infections. The gastrointestinal (GI) manifestations of CVID are rare and variable. We herein report the case of a patient with a severe hypocalcemia secondary to digestive tract involvement of the CVID syndrome.Case report: A 32 year-old female patient ...

Introduction: Pheochromocytomas are uncommon neuroendocrine tumors arising from chromaffin cells of the adrenal medulla. The aim of our study was to assess imaging characteristics of pheochromocytomas.Methods: The study was a retrospective analysis of 23 patients with pheochromocytomas. All participants had a computed tomography scan (CT). Several clinical and radiologic features were statistically analysed.Results: The Mean age wa...

Introduction: Hypoglycemia in non-diabetic patients is a rare condition. Because of the non-specificity of its symptoms and the multiplicity of its causes, hypoglycemia represents often a diagnostic challenge for general practitioners. The aim of our study was to assess the clinical features of hypoglycemia and to determine its causes in non-diabetic patients.Methods: We conducted a retrospective analysis in 49 non-diabetic patients who were admitted to ...

Background: Cardiovascular stratification and prevention in type 2 diabetic patients represent a major public health preoccupation in order to reduce their mortality. Several methods of detecting atherosclerosis have been developed such as biomarkers. The aim of this study was to evaluate the association between B-type natriuretic peptide (BNP) and cardiovascular risk (CVR) in type 2 diabetic patients.Methods: We conducted a cross-sectional study in 71 t...

Introduction: Sheehan’s syndrome (SS) is defined as partial or complete hypopituitarism occurring due to massive postpartum uterine hemorrhage that leads to pituitary infarction. Patients with SS have varying degrees of anterior pituitary hormone deficiency. The aim of our study was to evaluate the clinical and hormonal characteristics of patients with SS.Methods: Eighteen patients with SS were enrolled in a retrospective and descriptive study. Medi...

Introduction: Sheehan’s syndrome (SS) is postpartum hypopituitarism caused by necrosis of the pituitary gland. Patients with SS have varying degrees of anteriorpituitary hormone deficiency and have an increased mortality from cardiovascular disease. Inadequate hormone replacement is one of the possible causes of this increased mortality. The aim of our study was to assess metabolic and cardiovascular outcome in patients with SS.Methods: In a retrosp...

Introduction: Pituitary metastases are rare complications of malignancy, representing only 1% of surgical tumours of the pituitary gland. They are usually encountered in elderly patients with disseminated malignant disease. The most frequent are metastases of breast and lung cancer. In this report, we describe a rare case of a metastatic breast cancer to the pituitary gland.Observation: A 32-year-old female presented with blurred vision and diminished vi...